Tadaatsu Imaizumi Selected Research

Tretinoin (Retinoic Acid)

2/2022	Hepatic Macrophages Express Melanoma Differentiation-Associated Gene 5 in Nonalcoholic Steatohepatitis.
1/2021	PolyIC Induces Retinoic Acid-inducible Gene-I and Melanoma Differentiation-associated Gene 5 and Modulates Inflammation in Podocytes.
1/2019	Cytosolic Sensors of Viral RNA Are Involved in the Production of Interleukin-6 via Toll-Like Receptor 3 Signaling in Human Glomerular Endothelial Cells.
1/2017	Cylindromatosis (CYLD), a Deubiquitinase, Attenuates Inflammatory Signaling Pathways by Activating Toll-Like Receptor 3 in Human Mesangial Cells.
1/2017	DEC1 negatively regulates the expression of CXCL10 and CCL5 induced by poly IC in normal human mesangial cells.
1/2016	Interferon (IFN)-Induced Protein 35 (IFI35), a Type I Interferon-Dependent Transcript, Upregulates Inflammatory Signaling Pathways by Activating Toll-Like Receptor 3 in Human Mesangial Cells.
11/2015	Retinoic acid-inducible gene-I-like receptor (RLR)-mediated antiviral innate immune responses in the lower respiratory tract: Roles of TRAF3 and TRAF5.
10/2015	Toll-like receptor 3 signaling contributes to the expression of a neutrophil chemoattractant, CXCL1 in human mesangial cells.
2/2015	Tumor necrosis factor-α synergistically enhances polyinosinic-polycytidylic acid-induced toll-like receptor 3 signaling in cultured normal human mesangial cells: possible involvement in the pathogenesis of lupus nephritis.
7/2014	ISG54 and ISG56 are induced by TLR3 signaling in U373MG human astrocytoma cells: possible involvement in CXCL10 expression.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Tadaatsu Imaizumi Research Topics

Disease

22	Melanoma (Melanoma, Malignant) 02/2022 - 09/2005
21	Virus Diseases (Viral Diseases) 10/2022 - 08/2004
13	Lupus Nephritis 12/2022 - 08/2007
13	Hypoxia (Hypoxemia) 01/2017 - 04/2002
12	Inflammation (Inflammations) 12/2021 - 01/2006
9	Alzheimer Disease (Alzheimer's Disease) 06/2022 - 06/2002
8	Glomerulonephritis 11/2020 - 03/2008
8	Neoplasms (Cancer) 01/2020 - 04/2002
8	Astrocytoma (Pilocytic Astrocytoma) 01/2018 - 06/2007
6	Infections 12/2021 - 01/2007
6	Neuroblastoma 01/2018 - 02/2013
4	Systemic Lupus Erythematosus (Libman-Sacks Disease) 12/2022 - 04/2019
4	Chronic Renal Insufficiency 09/2021 - 01/2017
4	Parkinson Disease (Parkinson's Disease) 10/2015 - 06/2002
3	Aortic Valve Stenosis (Aortic Stenosis) 02/2021 - 11/2019
3	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2018 - 10/2015
3	Atherosclerosis 01/2017 - 04/2007
3	Mouth Neoplasms (Oral Cancer) 07/2011 - 05/2004
2	Autoimmune Diseases (Autoimmune Disease) 07/2022 - 11/2010
2	Rheumatoid Arthritis 01/2021 - 01/2009
2	Nephrotic Syndrome (Syndrome, Nephrotic) 01/2021 - 10/2017
2	Thrombosis (Thrombus) 01/2020 - 04/2019
2	Nephritis 01/2018 - 12/2011
2	Purpura 01/2018 - 12/2011
2	Hepatocellular Carcinoma (Hepatoma) 01/2017 - 05/2014
2	IGA Glomerulonephritis (IGA Nephropathy) 12/2015 - 10/2015
2	Neuroinflammatory Diseases 05/2015 - 07/2014
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2014 - 01/2006
2	Porcine Reproductive and Respiratory Syndrome (PRRS) 01/2012 - 02/2011
2	Carcinoma (Carcinomatosis) 07/2007 - 08/2004
2	Necrosis 01/2006 - 12/2002
1	Nervous System Diseases (Neurological Disorders) 06/2022
1	Disease Progression 02/2022

Drug/Important Bio-Agent (IBA)

27	Tretinoin (Retinoic Acid)FDA LinkGeneric 02/2022 - 08/2004
15	Poly I-CIBA 01/2021 - 08/2004
14	Antiviral Agents (Antivirals)IBA 12/2021 - 09/2005
14	Proteins (Proteins, Gene)FDA Link 12/2021 - 04/2002
13	Toll-Like Receptor 3IBA 12/2022 - 01/2013
12	Messenger RNA (mRNA)IBA 01/2022 - 04/2002
11	InterferonsIBA 12/2022 - 02/2007
9	Interferon Type IIBA 12/2022 - 07/2008
9	Double-Stranded RNA (RNA, Double Stranded)IBA 01/2019 - 08/2004
8	RNA Helicases (RNA Helicase)IBA 01/2021 - 07/2006
7	ChemokinesIBA 01/2021 - 01/2006
7	CytokinesIBA 12/2019 - 02/2007
6	Chemokine CX3CL1IBA 11/2020 - 12/2002
6	Amyloid beta-PeptidesIBA 01/2018 - 06/2002
6	Amyloid (Amyloid Fibrils)IBA 01/2018 - 06/2002
6	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 02/2008 - 07/2002
5	Viral RNAIBA 01/2019 - 09/2005
5	Peptides (Polypeptides)IBA 01/2018 - 02/2013
4	Toll-Like Receptors (Toll-Like Receptor)IBA 12/2022 - 01/2013
4	salvinIBA 05/2015 - 04/2011
4	Interferon-gamma (Interferon, gamma)IBA 01/2014 - 08/2003
4	RNA (Ribonucleic Acid)IBA 01/2013 - 01/2007
3	Plasminogen Activator Inhibitor 1IBA 01/2022 - 04/2002
3	Chloroquine (Aralen)FDA LinkGeneric 12/2021 - 11/2017
3	AcidsIBA 01/2021 - 06/2007
3	LigandsIBA 01/2018 - 02/2015
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2015 - 02/2007
3	Pattern Recognition ReceptorsIBA 12/2012 - 02/2011
3	Nerve Growth Factor (NGF)IBA 04/2011 - 01/2005
3	EdaravoneIBA 04/2011 - 12/2007
3	1-phenyl-3,3-dimethyltriazene (PDT)IBA 07/2007 - 05/2004
3	alpha-SynucleinIBA 06/2007 - 06/2002
2	tryptanthrineIBA 10/2022 - 01/2021
2	Pharmaceutical PreparationsIBA 07/2022 - 07/2011
2	Interleukin-6 (Interleukin 6)IBA 06/2022 - 01/2019
2	Antimalarials (Antimalarial Agents)IBA 12/2021 - 04/2019
2	Interferon Regulatory Factor-3 (Interferon Regulatory Factor 3)IBA 09/2021 - 01/2006
2	Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA 01/2021 - 10/2017
2	Rituximab (Mabthera)FDA Link 01/2021 - 10/2017
2	Vitamin K FDA Link 01/2020 - 11/2019
2	Interleukin-8 (Interleukin 8)IBA 01/2020 - 01/2007
2	Warfarin (Coumadin)FDA LinkGeneric 01/2020 - 11/2019
2	ImmunosorbentsIBA 01/2019 - 02/2015
2	EnzymesIBA 01/2019 - 02/2015
2	ResveratrolIBA 01/2018 - 01/2018
2	gnetin CIBA 01/2018 - 01/2018
2	Chemotactic FactorsIBA 01/2018 - 01/2014
2	Toll-Like Receptor 4IBA 08/2017 - 08/2013
2	Basic Helix-Loop-Helix Transcription FactorsIBA 01/2017 - 02/2008
2	CholesterolIBA 01/2017 - 10/2009
2	Small Interfering RNA (siRNA)IBA 01/2016 - 09/2011
2	IronIBA 05/2015 - 08/2003
2	Deferoxamine (Desferal)FDA LinkGeneric 05/2015 - 08/2003
2	Chelating AgentsIBA 05/2015 - 08/2003
2	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 02/2015 - 01/2014
2	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 02/2014 - 02/2013
2	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 01/2014 - 12/2013
2	mizoribineIBA 01/2014 - 12/2012
2	ChromatinIBA 12/2007 - 01/2007
2	Photosensitizing Agents (Photosensitizers)IBA 07/2007 - 01/2006
2	Talaporfin (talaporfin sodium)IBA 07/2007 - 01/2006
2	Plasminogen Activators (Plasminogen Activator)IBA 08/2003 - 04/2002
1	AntigensIBA 02/2022
1	Protein Isoforms (Isoforms)IBA 12/2021
1	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 12/2021

Therapy/Procedure

5	Therapeutics 10/2017 - 01/2006
2	Photochemotherapy (Photodynamic Therapy) 07/2007 - 01/2006